The Food and Drug Administration is warning women that a surgical procedure to remove noncancerous growths from the uterus could inadvertently spread cancer to other parts of the body.
The agency is discouraging doctors from performing the procedure, which uses an electronically powered device to grind and shred uterine tissue so it can be removed through a small incision in the abdomen. Known as laparoscopic power morcellation, the technique is widely used to treat painful fibroids, either by removing the growths themselves or the entire uterus.
Read more: http://www.laboratoryequipment.com/news/2014/04/growth-removal-procedure-can-actually-spread-cancer
Microscope Will Help Early Detection of Cancer, Diseases
An engineering researcher at the Univ. of Arkansas has developed an inexpensive, endoscopic microscope capable of producing high-resolution, sub-cellular images of tissue in real time. The fiber-optic device, which is portable, re-usable and easily packaged with conventional endoscopes, will help clinicians detect and diagnose early-stage disease, primarily cancer.
An endoscopic microscope is a tool or technique that obtains histological images from inside the human body in real-time. Some clinicians consider it an optical biopsy. The system, developed by Timothy Muldoon, assistant professor of biomedical engineering, also serves as an intraoperative monitoring device by providing a “preview of biopsy” – that is, helping clinicians target ideal locations on lesions prior to and during surgical biopsies – and by capturing high-resolution images of tumor margins in real time. The latter will help surgeons know whether they have totally removed a tumor.
Read more: http://www.laboratoryequipment.com/news/2014/04/microscope-will-help-early-detection-cancer-diseases
Nanoparticles Deliver Three Cancer Drugs
Delivering chemotherapy drugs in nanoparticle form could help reduce side effects by targeting the drugs directly to the tumors. In recent years, scientists have developed nanoparticles that deliver one or two chemotherapy drugs, but it has been difficult to design particles that can carry any more than that in a precise ratio.
Now, MIT chemists have devised a new way to build such nanoparticles, making it much easier to include three or more different drugs. In a paper published in the Journal of the American Chemical Society, the researchers showed that they could load their particles with three drugs commonly used to treat ovarian cancer.
Read more: http://www.laboratoryequipment.com/news/2014/04/nanoparticles-deliver-three-cancer-drugs
Cooperation in Cell Subpopulation Spur Tumor Growth
Subpopulations of breast cancer cells sometimes cooperate to aid tumor growth, according to Penn State College of Medicine researchers, who believe that understanding the relationship between cancer subpopulations could lead to new targets for cancer treatment.
Cancers contain genetically different subpopulations of cells, called subclones. Researchers have long known that these mutant subclones aggressively compete with one another to become the dominant tumor cell population. However, in some cases it seems that no single subclone can achieve dominance on its own.
Read more: http://www.laboratoryequipment.com/news/2014/04/cooperation-cell-subpopulation-spur-tumor-growth
Researchers at the Univ. of Montreal and the INRS-Institut-Armand-Frappier have shown that men circumcised after the age of 35 are 45 percent less likely to develop prostate cancer than uncircumcised men. This is one of the findings that resulted from a study undertaken by Andrea Spence and her research directors Marie-Élise Parent and Marie-Claude Rousseau. The researchers interviewed 2,114 men living on the Island of Montreal. Half of them had been diagnosed with prostate cancer between 2005 and 2009, while the others participated in the study as the control group. The questions covered their lifestyle and medical history, if they were circumcised, and if so, the age at which the operation had been performed.
Read more: http://www.laboratoryequipment.com/news/2014/04/adult-circumcision-could-prevent-cancer
Obama Honors Memory of Girl with Cancer Research Bill
A 10-year-old girl who died of brain cancer is leaving a legacy for other sick children in a new law signed by President Barack Obama.
Obama signed the bipartisan Gabriella Miller Kids First Research Act. It directs $126 million in federal money to be spent over the next decade to research pediatric cancer and other childhood disorders. Her parents and brother watched Obama sign the bill.
Read more: http://www.laboratoryequipment.com/news/2014/04/obama-honors-memory-girl-cancer-research-bill
Nanoballoons, Lasers Team to Fight Cancer
Chemotherapeutic drugs excel at fighting cancer, but they’re not so efficient at getting where they need to go. They often interact with blood, bone marrow and other healthy bodily systems. This dilutes the drugs and causes unwanted side effects.
Now, researchers are developing a better delivery method by encapsulating the drugs in nanoballoons, tiny modified liposomes that — upon being struck by a red laser — pop open and deliver concentrated doses of medicine.
Read more: http://www.laboratoryequipment.com/news/2014/04/nanoballoons-lasers-team-fight-cancer
Nanoparticles Force Cancer to Self-destruct
Using magnetically controlled nanoparticles to force tumor cells to self-destruct sounds like science fiction, but could be a future part of cancer treatment, according to research from Lund Univ.
“The clever thing about the technique is that we can target selected cells without harming surrounding tissue. There are many ways to kill cells, but this method is contained and remote-controlled,” says Prof. Erik Renström.
Read more: http://www.laboratoryequipment.com/news/2014/04/nanoparticles-force-cancer-self-destruct
A derivative of vitamin A, known as retinoic acid, found abundantly in sweet potato and carrots, helps turn pre-cancer cells back to normal healthy breast cells, according to research published this month in the International Journal of Oncology. The research could help explain why some clinical studies have been unable to see a benefit of vitamin A on cancer: the vitamin doesn’t appear to change the course of full-blown cancer, only pre-cancerous cells, and only works at a very narrow dose.
Read more: http://www.laboratoryequipment.com/news/2014/03/vitamin-may-reverse-pre-cancerous-cells
Organic Food Doesn’t Lower Cancer Risk
Women who always or mostly eat organic foods have the same likelihood of developing cancer as women who eat conventionally produced foods, according to an Oxford Univ. study.
Kathryn Bradbury and colleagues in Oxford’s Cancer Epidemiology Unit found no evidence that regularly eating a diet that was grown free from pesticides reduced a woman’s overall risk of cancer.
Read more: http://www.laboratoryequipment.com/news/2014/03/organic-food-doesnt-lower-cancer-risk
Substance Makes Cancer Explode
Researchers at Karolinska Institutet have discovered that a substance called Vacquinol-1 makes cells from glioblastoma, the most aggressive type of brain tumor, literally explode. When mice were given the substance, which can be given in tablet form, tumor growth was reversed and survival was prolonged. The findings are published in the journal Cell.
The established treatments that are available for glioblastoma include surgery, radiation and chemotherapy. But even if this treatment is given the average survival is just 15 months. It is therefore critical to find better treatments for malignant brain tumors.
Read more: http://www.laboratoryequipment.com/news/2014/03/substance-makes-cancer-explode
Researchers at the Univ. of North Carolina School of Medicine have devised a new biochemical technique that will allow them and other scientists to delve much deeper than ever before into the specific cellular circuitry that keeps us healthy or causes disease.
The method – developed in the lab of Klaus Hahn and described in the journal Nature Chemical Biology – helps researchers study how specific proteins called kinases interact to trigger a specific cellular behavior, such as how a cell moves. These kinase interactions are extraordinarily complex, and their interactions remain largely unknown. But researchers do know that kinases are crucial operators in disease.
Read more: http://www.laboratoryequipment.com/news/2014/03/technique-may-unravel-mysteries-metastasis
Anti-psychotic Meds Kill Tumors
Researchers at UC San Diego School of Medicine have discovered that FDA-approved anti-psychotic drugs possess tumor-killing activity against the most aggressive form of primary brain cancer, glioblastoma. The finding was published in Oncotarget.
The team of scientists, led by principal investigator, Clark Chen, vice-chairman, UC San Diego School of Medicine, division of neurosurgery, used a technology platform called shRNA to test how each gene in the human genome contributed to glioblastoma growth. The discovery that led to the shRNA technology won the Nobel Prize in Physiology/Medicine in 2006.
Read more: http://www.laboratoryequipment.com/news/2014/03/anti-psychotic-meds-kill-tumors
Meat, Cheese May Be as Bad as Smoking
That chicken wing you’re eating could be as deadly as a cigarette. In a new study that tracked a large sample of adults for nearly two decades, researchers have found that eating a diet rich in animal proteins during middle age makes you four times more likely to die of cancer than someone with a low-protein diet — a mortality risk factor comparable to smoking.
“There’s a misconception that because we all eat, understanding nutrition is simple. But the question is not whether a certain diet allows you to do well for three days, but can it help you survive to be 100?” says corresponding author Valter Longo, professor of biogerontology at the Univ. of Southern California Davis School of Gerontology and director of the USC Longevity Institute.
Read more: http://www.laboratoryequipment.com/news/2014/03/meat-cheese-may-be-bad-smoking
Ancient Chinese Medicine Joins Cancer Fight
The bark of the Amur cork tree (Phellodendron amurense) has traveled a centuries-long road with the healing arts. Now, it is being put through its paces by science in the fight against pancreatic cancer, with the potential to make inroads against several more.
Univ. of Texas Health Science Center at San Antonio researcher A. Pratap Kumar was already exploring the cork tree extract’s promise in treating prostate cancer when his team found that deadly pancreatic cancers share some similar development pathways with prostate tumors.
Read more: http://www.laboratoryequipment.com/news/2014/03/ancient-chinese-medicine-joins-cancer-fight