Scientists See 3D Structure of Drug Target for Diabetes
An international team led by scientists at The Scripps Research Institute (TSRI) has determined and analyzed the three-dimensional atomic structure of the human glucagon receptor. The receptor, found mainly on liver and kidney cells, helps regulate glucose levels in the bloodstream and is the target of potential therapeutic agents for type 2 diabetes.
“Our data should change the current view of how drugs are designed with this and related receptors,” says TSRI Research Associate Fai Yiu Siu, the first author of the study.
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