Cell Counters Accelerate Immune System Research
The availability of simplified methods for identifying the activation status of cells has accelerated research in the field of immune responsiveness concerning viral, bacterial, cellular and environmental exposure.
Biological samples such as primary isolates or cultured cells are often heterogeneous mixtures of cells that differ by type and/or function. Such differences in cellular attributes are most commonly determined by multicolor fluorescent antibody detection of cell type specific surface marker(s) using flow cytometry. In addition to variations in protein expression, many cell types and physiological states are also uniquely distinguishable on the basis of size alone. The ability to identify population subsets on the basis of phenotypic differences and further determine their relative frequencies and concentrations is critical to many aspects of research.
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